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Eupatorium perfoliatum (boneset or agueweed)
Eupatorium is one of the greatest flu remedies when the main symptom is pain in the bones instead of the muscles. There is fever with bone aches, " as if the bones would break. " There is also outspoken stiffness of the whole body, with a bruised feeling (Arnica), restlessness and intense thirst for cold water (Aconite).